Signaling to p53: Ribosomal Proteins Find Their Way
نویسندگان
چکیده
منابع مشابه
Signaling to p53: ribosomal proteins find their way.
Inherently disparate cell growth and division, which are intimately coupled through a delicate network of intracellular and extracellular signaling, require ribosomal biogenesis. A number of events imparting instability to ribosomal biogenesis can cause nucleolar stress. In response to this stress, several ribosomal proteins bind to MDM2 and block MDM2-mediated p53 ubiquitination and degradatio...
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ژورنال
عنوان ژورنال: Cancer Cell
سال: 2009
ISSN: 1535-6108
DOI: 10.1016/j.ccr.2009.09.024